Physicochemical characterization of six monoclonal cryoimmunoglobulins: possible basis for cold-dependent insolubility.

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Physicochemical characterization of six monoclonal cryoimmunoglobulins: possible basis for cold-dependent insolubility.

The physical and chemical properties of five human and one canine monoclonal cryoimmunoglobulin have been compared. By many criteria, the proteins cannot be distinguished from the noncryoglobulin reference proteins analyzed in parallel; however, certain hydrodynamic and spectroscopic properties of the proteins indicate that cryoimmunoglobulins differ in tertiary structure relative to their cold...

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ژورنال

عنوان ژورنال: Proceedings of the National Academy of Sciences

سال: 1978

ISSN: 0027-8424,1091-6490

DOI: 10.1073/pnas.75.7.3440